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9 capsules

Drug Research Bias: Ghostwriting, Trial Data, and Patient Protection

Drug Research Bias: Ghostwriting, Trial Data, and Patient Protection

The research behind your medications may carry hidden ghostwriters and massaged trial data. The views split on the remedy: exposing manipulated studies one by one, forcing legal and regulatory reform on the companies, or practicing evidence-based care that routes around the bias, especially for vulnerable patients. Decide how much to trust drug claims and how to protect yourself in the meantime.

Pharmaceutical industry · 78 stops · ~156 minFree
The Replication Crisis: Preregistration, Statistics, Transparency, and Incentives

The Replication Crisis: Preregistration, Statistics, Transparency, and Incentives

The replication crisis has exposed how fragile published findings can be when studies are repeated under closer scrutiny. This overview explains the roles of preregistration, statistical thresholds, trial transparency, and professional incentives in shaping research reliability. Readers will understand the main reform proposals, their tradeoffs, and why the debate over whether science can correct itself remains unresolved.

Replication crisis · 99 stops · ~198 minFree
Sleep Trackers and Clinical Sleep Studies: Uses, Limits, and Decisions

Sleep Trackers and Clinical Sleep Studies: Uses, Limits, and Decisions

Sleep trackers and clinical sleep studies serve different purposes in understanding rest, fatigue, and possible sleep disorders. Readers will learn how consumer devices estimate patterns, how laboratory studies measure sleep and support diagnosis, and how to judge when self-tracking is sufficient versus when professional assessment is warranted.

Sleep trackers · 62 stops · ~124 minFree
Gut Microbiome Testing: Reliability, Regulation, and Diet Decisions

Gut Microbiome Testing: Reliability, Regulation, and Diet Decisions

Despite popular marketing, gut microbiome tests lack FDA approval and clinical reliability, making them unsuitable for diagnosing conditions or guiding diet changes. The mainstream hype suggests these tests offer personalized health insights, but experts warn against making lifestyle or medical decisions without professional advice. Following this cautious approach helps avoid ineffective or potentially harmful self-prescribed treatments based on unproven test results.

Gut health · 63 stops · ~126 minFree
A SaaS Founder’s Guide to Freemium, Trials, and Demos

A SaaS Founder’s Guide to Freemium, Trials, and Demos

Whether you give the product away, hand out a trial, or run a demo reshapes your whole sales motion. These options differ on whether users can self-activate cheaply enough for freemium, whether fast trial activation lifts conversions, or whether a tailored demo that hits real pain points closes better. Weigh them against your product's complexity and cost to serve.

B2B SaaS · 48 stops · ~96 minFree
Peter Attia's Outlive: Longevity Guidelines, Evidence, and Tradeoffs

Peter Attia's Outlive: Longevity Guidelines, Evidence, and Tradeoffs

Longevity medicine offers varied guidelines on exercise intensity, supplement timing, medical screening, and cold exposure. These guidelines differ on how to balance rigorous research with practical daily actions, when to intervene medically, and how to safely apply cold therapies. Understanding these differences helps you choose personalized strategies for healthspan and lifespan optimization.

Longevity · 62 stops · ~124 minFree
Gut Microbes and Mood: Weighing the Evidence

Gut Microbes and Mood: Weighing the Evidence

The gut-brain link is exciting, but whether your microbes cause mood changes or just correlate with them decides how much to trust probiotics. These views differ on demanding strict standardized trials, tightening safety and protocol, and sharpening methods to capture how gut and brain actually talk. Weigh them to judge how confident to be in gut-based treatments.

Gut microbiome · 73 stops · ~146 minFree
Intermittent Fasting and Weight Loss: Evidence, Benefits, and Risks

Intermittent Fasting and Weight Loss: Evidence, Benefits, and Risks

Intermittent fasting is sold as a shortcut, but head-to-head it doesn't clearly beat plain old calorie control for weight loss. Some trials show perks like better insulin sensitivity, yet the rigorous evidence finds no meaningful difference on the scale. Focus on sustainable eating, and check with a professional before you try fasting.

Intermittent fasting · 55 stops · ~110 minFree
Transcendental Meditation and Mindfulness: Stress, Focus, and Evidence

Transcendental Meditation and Mindfulness: Stress, Focus, and Evidence

Transcendental Meditation and mindfulness both promise real change, but they may help different things. These claims compare where the evidence favors TM for lowering stress-related physical risk versus mindfulness for daily focus and emotional control, and where head-to-head proof runs thin. You can decide which practice fits the results you are after.

Meditation · 60 stops · ~120 minFree